Dr Damian C Crowther

Damian has had a lifelong passion for computing—he founded his first software company at just 15 and helped develop patient record software for General Practice.

He also took the lead in designing and developing this website.

His academic career began with graduating top of his class in Natural Sciences at the University of Cambridge, followed by a PhD in protein engineering of serine protease inhibitors. Damian then attended the Clinical School at Oxford University, where he was awarded the Hobson Memorial Scholarship for Clinical Medicine before graduating in 1995. He completed his early clinical training in Oxford, Barrow-in-Furness, and later Nottingham.

Upon returning to Cambridge at the turn of the century, Damian co-founded and co-wrote GPnotebook.com. A Wellcome Trust Advanced Clinical Training Fellowship allowed him to balance clinical work with leading a basic neuroscience research group. Focused on understanding how oligomeric protein aggregates drive neurodegeneration—particularly Alzheimer’s—his team employed both in vitro and invertebrate models.

In 2015, Damian moved into commercial neuroscience R&D, joining AstraZeneca as a Director in Neuroscience and ultimately becoming Head of Drug Discovery. In 2020 he was elected Fellow of the Royal College of Physicians. Within a year he had returned to his entrepreneurial roots to co-found TRIMTECH therapeutics, leveraging 15 years of targeted protein degradation research at the Laboratory of Molecular Biology and the University of Cambridge. TRIMTECH’s technology selectively eliminates toxic intracellular protein aggregates while preserving essential, functional proteins, opening new avenues in the treatment of neurodegenerative disorders.