Round Up Email July 2024

a systematic review concluded that aspirin appears to be effective at reducing the incidence of colonic adenoma and colorectal cancer, especially if used in high doses for more than 10 years

there is evidence about the effectiveness of both low dose and high dose aspirin in the prevention of colorectal cancer

there is no evidence of benefit of aspirin in the prevention of further instance of colorectal cancer in patients with a history of prior colorectal cancer

evidence for the use of domperidone in the management of insufficient milk supply during breast feeding shows a moderate short-term effect on expressed breast milk volume, increasing by around 86 to 245mL per day

duration of treatment for 28 days is in line with the maximum treatment duration for the licensed indication (nausea and vomiting), due to the increased risk of cardiac events (particularly in certain populations), and potential for psychiatric withdrawal effects

cardiac events in the infant have not been reported after domperidone exposure via breast milk

study evidence has shown that in an eldery population, remaining active over the eight year period of the study conferred a seven times increased chance of an individual being healthy in old age compared to his/her inactive peers

WHO guidance for exercise in people over the age of 65 years suggests muscle-strengthening activities should be done on four or more days

evidence suggest that power training (lifting weights fast and lowering under control) was associated with a modest improvement in physical function compared with traditional strength training in healthy, community-living older adults

study evidence showed that eight weeks of acupuncture were superior to sham acupuncture in reducing methadone dose and decreasing opioid craving

in a systematic review and meta-analysis of randomised and observational studies of buprenorphine versus methadone for the treatment of opioid dependence found, at timepoints beyond 1 month, retention in treatment was better for methadone vs buprenorphine

in a systematic review and meta-analysis of randomised and observational studies of buprenorphine versus methadone for the treatment of opioid dependence found evidence of increased hospitalisation and alcohol use in people receiving methadone

the RSV vaccine in pregnancy boosts the maternal immune system to produce more antibodies against the virus and these antibodies then pass through the placenta to help protect the unborn child from the day they are born

women will be offered the RSV vaccination during every pregnancy

pevious RSV infection confers total immunity to RSV

in tennis elbow, steroid injections have been shown to improve short-term pain relief (4 to 6 weeks) compared with both placebo and bracing

evidence suggests the long-term benefits of steroid injection for tennis elbow in comparison to physiotherapy

hydrocortisone acetate mixed with local anaesthetic may be used, and long acting steroids should be avoided as there is a risk of skin atrophy