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Side effects

Authoring team

Adverse effects include:

  • hypo's:
    • hypotension and dehydration
    • hypokalaemia or magnesaemia
    • hyponatremia
    • hypochloraemia
    • impotence

  • hyper's:
    • hyperkalaemia
    • hyperuricaemia and gout
    • hyperglycaemia and diabetes
    • hypercalcaemia
    • hypercholesterolaemia

  • others:
    • renal impairment
    • antiandrogenic effect - spironolactone
    • renal stones - triamterene
    • alkalosis, which further limits potassium retention

Reference

  1. Jackson EK. Drugs affecting renal excretory function. In, Brunton LL, Hilal-Dandan R, Knollman BC, eds. Goodman & Gilman’s the pharmacological basis of therapeutics. 13th ed. New York: McGraw-Hill, 2018, pp. 445-70.

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