Results
The median age of those enrolled was:
- 85 years for men
- 86 years for women
Cerebrovascular disease was seen in 78% of individuals. Alzheimer's disease pathology was seen in 70% of individuals.
Dementia was diagnosed in 48% of cases, of which the diagnosis was Alzheimer's disease in 64%.
There was a broad overlap in pathology between the demented and non-demented groups:
- severe neocortical neuritic plaques were seen in:
- 35% of the demented group
- 5% of the non-demented group
- moderate or severe neurofibrillay pathology was seen in:
- 39% of the demented group
- 8% of the non-demented group
- multiple vascular disease lesions were seen in:
- 46% of the demented group
- 33% of the non-demented group
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