Drug-induced hypertrichosis
Causes include:
- streptomycin - increased hair growth in children (of both sexes) has been reported
- diphenylhydantoin - hypertrichosis seen more in females
- corticosteroids - facial hypertrichosis may result from prolonged or intensive therapy
- penicillamine - associated with hypertrichosis affecting the trunk and limbs
- psoralens - may induce temporary hypertrichosis on light-exposed areas
- diazoxide - hypertrichosis occurs in 50-100% of children treated. However less than 1% of adults develop hypertrichosis. This drug may cause hypertrichosis via vasodilatory action
- minoxidil - also a potent vasodilator
- cyclosporin A - results in an increase in hair growth in 44% of patients treated. Hypertrichosis is reversible on discontinuation of therapy.
- interferon- alpha
- phenytoin
- spironolactone
- zidovudine
Reference:
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