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Melanocyte

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Melanocytes are neural crest-derived cells found in the epidermal stratum basale and stratum spinosum of the skin, in hair bulbs, pia arachnoid and the retina. They are spindle-shaped and possess dendritic processes.

They are unique in their synthesis of melanin, which is one element in the formation of skin colour. Melanin has a protective role, absorbing and dispersing the sun's rays, and mopping up free radicals.

Melanocytes can derive a number of neoplasms, both benign and malignant. Malignant melanoma has doubled in incidence in the last twenty years.

Reference

  1. Chichorek M. Skin melanocytes: biology and development. Postepy Dermatol Alergol. 2013 Feb;30(1):30-41.

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