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Investigations

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The investigation of a suspected case of pyoderma gangrenosum should include:

  • skin biopsy:
    • for culture to detect bacteria and fungi
    • for histology to detect malignancy and vasculitis

  • gastrointestinal imaging in selected patients:
    • barium meal and enema

  • blood tests to detect:
    • paraproteinaemia
    • antiphospholipid antibody
    • antinuclear antibody
    • ANCA

  • full blood count and blood smear
  • bone marrow examination in selected patients

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