Contraindications include:
The SPC for raloxifene advises that cholestyramine should not be given with raloxifene - cholestyramine reduces the absorption and enterohepatic circulation of raloxifene.
Raloxifene may cause a modest increase in prothrombin time in patients receiving warfarin or other coumarins - this should be checked for.
The summary of product characteristics must be checked before prescribing this drug.
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