Frequency of creatinine/eGFR testing
Kidney function should be measured at least annually in the risk groups below:
Previously diagnosed CKD, including
- polycystic kidney disease
- reflux nephropathy
- biopsy-proven chronic glomerulonephritis
- persistent proteinuria
- urologically unexplained persistent haematuria
Conditions associated with a high risk of obstructive nephropathy, including
- known or suspected bladder outflow obstruction
- neurogenic bladder caused by spina bifida or spinal cord injury (N.B. calculated GFR may overestimate true GFR in these patients because of decreased muscle mass)
- urinary diversion surgery
- urinary stone disease due to primary hyperoxaluria, cystinuria, Dent?s disease, infections (with struvite stones), anatomical abnormalities, or a stone episode rate of > 1/y Conditions known to be associated with a high risk of silent development of CKD, including
- hypertension
- diabetes mellitus
- heart failure
- atherosclerotic coronary, cerebral, or peripheral vascular disease
Conditions requiring long-term treatment with potentially nephrotoxic drugs, including
- ACEIs and ARBs
- NSAIDs
- lithium carbonate
- mesalazine and other 5-aminosalicylic acid drugs
- calcineurin inhibitors (Cyclosporin, Tacrolimus)
Multisystem diseases that may involve the kidney, including systemic lupus erythematosus (SLE), vasculitis, myeloma, rheumatoid arthritis
A first degree relative with stage 5 CKD
Minimum frequency of measurement of kidney function according to estimated GFR (2) :
How frequently do you need to measure eGFR?
Stage | eGFR range (ml/min/1.73 m^22) | Typical frequency of testing |
1 and 2 | > 60 + other evidence of kidney disease | 12 monthly |
3A and 3B | 30-59 | 6 monthly |
4 | 15-29 | 3 monthly |
5 | <15 | 6 weekly |
Reference:
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