Chronic DIC
The common causes of chronic disseminated intravascular coagulation (DIC) include:
- adenocarcinoma:
- a low grade DIC characteristically results in thrombophlebitis migrans and recurrent venous thromboembolism (Trousseau's syndrome)
- the mechanism of DIC includes tissue damage, secretion of tissue factor or secretion of other procoagulants
- retained dead foetus syndrome:
- initially this is a low grade DIC
- fulminant DIC will inevitably follow if the uterus is not evacuated
- liver disease:
- coagulopathy is characteristic of liver disease - DIC may play a part
- coagulopathy is characteristic of liver disease - DIC may play a part
- localised lesions:
- aneurysms
- haemangiomata (Kasabach-Meritt syndrome)
- empyema
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