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Pelger-Huet anomaly

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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This is an uncommon condition where bilobed neutrophils are found in the peripheral blood. There may be unsegmented neutrophils occasionally seen.

The Pelger-Huet anomaly may be:

  • congenital, inherited in an autosomal dominant manner
  • acquired, often in cases of myelodysplastic syndrome

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