This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

PRoFESS trial

Authoring team

The PRoFESS trial (1) compared the efficacy of two treatments in secondary prevention of stroke:

  • 25 mg aspirin (ASA) and 200 mg extended-release dipyridamole twice a day, with
  • 75 mg clopidogrel once a day

Both regimens resulted in similar rates of recurrent stroke.

Reference:

1. Diener HC et al. Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study. Lancet Neurol. 2008 Oct;7(10):875-84.

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.