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Side effects

Authoring team

  • hypotension - use IV fluids and raise legs
  • a very rare side effect is anaphylaxis
  • re-perfusion arrhythmias may occur eg ventricular fibrillation
  • bradycardia

There is no increase in the incidence of stroke.

Note - among all fibrinolytic agents, streptokinase is the most antigenic; thus, it is most frequently complicated by allergic reactions and hypotension

Reference

  1. Keramati M et al. Towards a superior streptokinase for fibrinolytic therapy of vascular thrombosis. Cardiovasc Hematol Agents Med Chem. 2013 Sep;11(3):218-29

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