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Intervention studies

Authoring team

There are few intervention studies into the consequences of H. pylori eradication on the incidence of gastric carcinoma.

A Japanese study of 132 H. pylori positive patients undergoing endoscopic resection of early gastric cancer compared the rates of recurrent gastric cancer in patients with or without H. pylori eradication:

  • 9% without eradication had recurrent cancer
  • 0% with eradication had recurrent cancer (p=0.01)

Reference:

  • Uemura, N, Mukai, T, Okamoto, S, et al. (1997). Effect of Helicobacter pylori eradication on subsequent development of cancer after endoscopic reseftion of early gastric cancer. Cancer Epidemiol Biomarkers Prev, 6, 639-42

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