Unusual manifestations
Unusual manifestations of Whipple's disease include:
- central nervous system:
- dementia
- ophthalmoplegia
- myoclonus
- oculomasticatory movements:
- convergent eye movements with simultaneous chewing movements
- convergent eye movements with simultaneous chewing movements
- cardiac:
- fibrous pericarditis
- myocarditis
- lesions of the mitral and aortic valves
- pulmonary:
- pleural effusion
- chronic cough
- mediastinal widening caused by adenopathy
- a sarcoidosis-like syndrome:
- the PCR test for T. whippelii should be used in patients with a diagnosis of sarcoidosis
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