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If the diagnosis is suspected appendicitis, the patient should be given broad-spectrum antibiotics. Many agents have been tried:
The timing of prophylaxis is vital. It should be given at induction. The duration of therapy is dependent on the operative findings. Generally, only a couple of doses of antibiotics are necessary for early, uncomplicated appendicitis. Those with a perforated or necrotic appendix or an appendix mass should be given a more prolonged course e.g. 7-10 days.
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