This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Holmes-Adie pupil

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The Holmes-Adie pupil is large and irregular.

Pupillary constriction:

  • to light is slow and incomplete
  • to accomodation is relatively normal
  • once the pupil has constricted it remains small for an abnormally long time (tonic pupil)

The Holmes-Adie pupil is considered a variation of normal but is rarely the result of a lesion in the efferent parasympathetic pathway.

The Holmes-Adie syndrome is the association of a Holmes-Adie pupil with absent deep tendon jerks.

Clinical features include:

  • unilateral in 80% of cases
  • dilated pupil in early stages
  • decreased consensual and direct light reflex
  • tonic pupil: pupil slowly constricts in bright light
  • decreased accommodation reflex
  • decreased tendon reflexes
  • hypersensitivity to G pilocarpine solution (0.12%)
  • patients are often young women

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.