Mosaicism
A mosaic organism is composed of two or more genetically different cell lines which are all derived from a single zygote.
The mosaicism derives from nondisjunction or chromosome lag during one of the mitoses during early embryogenesis.
The most common form of genetic mosaicism is disomy/trisomy mosaics for a particular chromosome; about 1% of Down's syndrome patients are disomy/trisomy mosaics for chromosome 21.
Polyploidy mosaics are occasionally found e.g. diploid/triploid mosaics.
Usually mosaics suffer a mild form of the disease associated with the aneuploid genome.
Related pages
Create an account to add page annotations
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.