CK in skeletal muscle disease
CK is raised in:
- muscular dystrophies - very high early in the early stages of Duchenne muscular dystrophy; levels decrease with time. There is an increased proportion of CK-MB.
- polymyositis
- rhabdomyolysis
- elevated levels are found in up to 40% of patients with motor neurone disease and in some other conditions associated with denervation
Note that strenuous exercise increases levels.
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