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CK in skeletal muscle disease

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CK is raised in:

  • muscular dystrophies - very high early in the early stages of Duchenne muscular dystrophy; levels decrease with time. There is an increased proportion of CK-MB.
  • polymyositis
  • rhabdomyolysis
  • elevated levels are found in up to 40% of patients with motor neurone disease and in some other conditions associated with denervation

Note that strenuous exercise increases levels.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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