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In renal impairment

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

As for any prescribing in renal impairment, appendix III in the BNF should be consulted.

Renal impairment is common, increasing in the elderly. Toxicity occurs frequently and is avoidable. Mechanisms include:

  • diminished renal excretion
  • plasma protein binding
  • altered drug action, e.g. CNS depressants, hypotensive vasodilators, anticoagulants, NSAIDS, acetylcholinesterase inhibitors.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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