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Drugs prescribed according to NYHA class

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The use of major classes of drugs in the control of HF according to NYHA class is as follows:

  • NYHA I - ACE inhibitor, beta blocker
  • NYHA II-III - ACE inhibitor, beta blocker, candesartan (intiation requires specialist advice)
  • NYHA III-IV - ACE inhibitor, beta blocker, spironolactone (intiation requires specialist advice)

Combination of an ACE inhibitor, an angiotensin receptor blocker and spirnolactone is not recommended since the safety and efficacy of combining these drugs is uncertain (1).


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