irrespective of whether the patient is to undergo cardiac surgery antibiotic therapy should be commenced
initially, a bacteriocidal combination of antibiotics should be administered intravenously
the choice of antibiotics, doses and duration of treatment are dependent upon the putative organism, the severity of the infection and its response to treatment.
the serum concentration of antibiotics should be measured and related to the minimum inhibitory concentration of the organism if this is known
renal function should be monitored throughout the course of antibiotic treatment and treatment may need adjusting accordingly
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