Clinical features
Key clinical features include:
- congestive heart failure, which appears in the neonatal period
- mild cyanosis
- systolic and diastolic murmurs originating from the truncal valve
The cardiac examination is notable for a harsh holosystolic murmur, an ejection click, a single loud second heart sound, and a diastolic murmur if truncal valve regurgitation is present. Peripheral pulses may be bounding due to excess runoff into the pulmonary arteries.
Other congenital anomalies, such as facial abnormalities and musculoskeletal defects, may be noted if truncus arteriosus is only part of a syndrome.
Reference
- Konstantinov IE et al. Truncus arteriosus associated with interrupted aortic arch in 50 neonates: a Congenital Heart Surgeons Society study. Ann Thorac Surg. 2006 Jan;81(1):214-22
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