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Larva therapy for venous leg ulceration

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • larvae are increasingly used to treat leg ulcers and are thought to stimulate healing, reduce bacterial load, and eradicate MRSA
    • however clinical evidence to support larval therapy comes from a small randomised controlled trial that did not follow patients to healing
  • a study using larval therapy for venous leg ulcers revealed
    • larval therapy significantly reduced the time to debridement of sloughy or necrotic leg ulcers compared with hydrogel
    • larval therapy did not increase healing rates nor reduce bacterial load and was associated with significantly more ulcer related pain in the 24 hours before removal of the first treatment than hydrogel

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