Last reviewed dd mmm yyyy. Last edited dd mmm yyyy
Pruritus associated with cholestasis secondary to primary biliary cirrhosis is managed with the following:
Use of ursodeoxycholic acid (UDCA) has been beneficial in cholestatic itch due to intrahepatic cholestasis of pregnancy (1).
Cholestyramine may reduce the absorption of vitamin D and so worsen osteomalacia. Consider UV light treatment or plasmapheresis, which also benefits xanthomata and xanthomatous neuropathy.
Cholestatic itch due to obstructive bile duct lesions is managed with either endoscopic, radiological or surgical correction treatment (1).
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