An ulcer is a localised defect in the continuity of an epithelial surface. It is usually associated with an inflamed base of granulation tissue with or without necrotic slough.
The majority are chronically inflamed; the slough at their base represents inadequate drainage. Acutely inflamed ulcers may have an outer rim of cellulitis.
Weak ulcers are those with low quality granulation tissue and hence delayed healing; they are usually due to ischaemia or infections such as tuberculosis.
Reference
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