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Pathology

Authoring team

The following histological features are found irrespective of the cause of the chronic active hepatitis:

  • intense portal inflammatory infiltrate which spills over into the liver parenchyma
  • piecemeal hepatocyte necrosis
  • bridging necrosis between adjacent triads
  • progressive fibrosis beginning in the portal triads and radiating into the liver parenchyma
  • the end-point is frank cirrhosis

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