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Thiazide and asymptomatic hyperuricaemia

Authoring team

  • occurs in up to 30% of hypertensive patients treated with thiazide diuretics

  • the presence of hyperuricaemia per se does not require withdrawal of the thiazide or treatment

  • if gout develops however then it is prudent to stop thiazide treatment and initiate alternative therapy for hypertension

  • if a patient has a history of gout then treatment with thiazides are best not used - if necessary concurrent treatment with allopurinol can allow continued treatment with a thiazide

Reference:

  • (1) Prescriber (2001), 12 (18), 49-61.

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