Helicobacter pylori
Helicobacter pylori (formerly named Campylobacter pylori) is a gram negative S shaped or spiral bacillus, described as a Unipolar flagellate, 1 by 3 micrometres in size. It is a microaerophilic, and produces urease and other toxins.
Infection with Helicobacter pylori is common in patients with peptic ulceration. A short course of standard ulcer treatment usually heals ulceration but about 85% of patients relapse within a year. In patients with duodenal ulcer, eradication of H. pylori causes the relapse rate to fall to 0 - 20%.
The best test for identification of H Pylori and for confirmation of eradication is the 13C urea breath test (1).
Reference:
- BSG (2002) Dyspepsia management guidelines.
- Drugs and Therapeutics Bulletin (1993); 31(4) 4: 15.
Related pages
- Associations
- Treatment of duodenal ulceration associated with H.pylori
- Helicobacter pylori and reflux oesophagitis
- 13C UREA breath test
- Helicobacter pylori testing and diagnosis
- Dyspepsia (H.pylori test and treat strategy)
- When is testing for H. pylori indicated?
- Helicobacter pylori triple therapy
- When is retesting for H pylori indicated?
- Helicobacter pylori triple therapy - based on whether penicillin allergic or not
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