Invasive salmonellosis (non enteric fever)
This is a form of non-typhoid salmonella infection characterised by bacteraemia and septicaemia. It is more likely to occur in infants, the elderly and the immunocompromised.
It may present with:
- a typhoid-like illness without significant diarrhoea or localising features
- severe diarrhoea with swinging high fever
- evidence of metastatic, extra-intestinal sites i.e. meninges, joints, lungs, spleen, kidneys, endocardium, atheromatous aorta and large vessels
- infants may develop meningitis and those with sickle cell anaemia may develop osteomyelitis
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