Cautions and side-effects
Cautions:
- hepatic and renal impairment
- elderly, young adults, and children
- may mask underlying disorders eg cerebral irritation
- avoid for 3-4 days after gastro-intestinal surgery
- acute hypertensive response in phaeochromocytoma
- pregnancy and breast-feeding
- porphyria
Side-effects:
- extrapyramidal effects (esp children/young adults)
- hyperprolactinaemia
- occasionally tardive dyskinesia if prolonged use
- also reported: drowsiness, restlessness, diarrhoea, depression, neuroleptic malignant syndrome; cardiac conduction abnormalities with i.v. administration
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