This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
account_circleSign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Dose

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The incidence of gastrointestinal side effects with metformin is lower if a small initial dose is used. BNF recommendations now advise a step-wise introduction of metformin treatment (1)

  • an initial dose of 500mg with breakfast for one week; then 500mg with breakfast and evening meal for one week; then 500mg with breakfast, lunch and evening meals

  • most physicians limit to a maximum total dose of 2g daily

Reference:

  • (1) Prescribers' Journal (2000), 40 (1), 38-48.
  • (2) BNF 6.1

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.