Transcellular fluid
Transcellular water is found in:
- cerebrospinal fluid
- the gastrointestinal tract
- the urinary tract
- the ducts of glands
- serous cavities
Transcellular water is also termed the 'third space'.
Pathologic third compartment fluid may be in:
- ileus fluid - can be the most acute in onset
- ascites
- pleural effusions
Transcellular fluid comes from the plasma and extracellular fluid; thus excessive expansion of the third space is an important cause of hypovolaemia and subsequent renal failure.
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