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Late clinical features

Authoring team

Clinical features of late syphilis do not usually occur until after 2 years of age. These take the form of stigmata relating to early damage to developing structures:

  • facial abnormalities including frontal bosses, saddle nose, protruding mandible, Hutchinson's teeth, facial gumma
  • sabre tibia - tibial periostitis
  • interstitial keratitis
  • eighth nerve deafness
  • periostitis and Clutton's joints
  • juvenile neurosyphilis
  • paroxysmal cold haemoglobulinuria

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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