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Microscopic

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The two most important features in the walls of atherosclerotic aneurysms are:

  • smooth muscle atrophy
  • loss of elastic laminae

The adventitia is compressed and is often the site of a lymphocytic infiltrate which may be a response to the presence in the lesion of oxidised lipid or 'ceroid'.

AAA has a familial pattern with a prominent genetic component. For reasons that are unclear, in population based studies, diabetics have a lower incidence of aneurysms than non diabetics (1).

Reference:

  • (1) British Heart Foundation (Factfile 2/2008). Abdominal aortic aneurysms.

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