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Pharmacology in the elderly

Authoring team

Of particular note in the handling of drugs in the elderly are:

  • metabolism: - liver function affected by illness, CCF, infections, dehydration, nutrition
  • difficult to identify specific drugs: - renal excretion - GFR falls with age. - particular problems with digoxin, aminoglycosides, lithium, procainamide, tetracyclines.
  • pharmacodynamic factors: - diminished responses to drugs

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