Most prominent signs according to age of individual with Klinefelter's syndrome
most prominent signs according to period of life in patients with Klinefelter’s syndrome
Birth
- cryptorchidism
- small penis
- scrotum bifidus
- hypospadia
- fifth finger clinodactily
- cleft palate
- inguinal hernia
- hypotonia
Infancy
- small testes
- small penis size
- speech and language deficits
- long legs and arms
Childhood
- speech and language deficits
- learning disabilities
- psychological difficulties
- behavioral issues
Puberty
- long legs and arms
- gynaecomastia
- sparse facial, body and pubic hair
- gradual increase of FSH and LH
Adulthood
- small and firm testes
- gynaecomastia
- sparse facial, body and pubic hair
- infertility
- sexual dysfunction
- metabolic syndrome
Reference:
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