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Of the 19 trials investigating the effect of HRT on the risk of colorectal cancer 15 show a beneficial effect.
The benefits are most marked amongst long term users:
Note though that more recent evidence, concerning use of conjugated equine oestrogen in women who have had a hysterectomy, did not show an increase in breast cancer, thromboembolic disease, colorectal cancer or heart disease in 6.8 years of use (3).
A review states that (4):