Indications for transfusion on thalassaemia intermedia
- haemoglobin concentration <5.0 g/dL
- falling haemoglobin level with profound enlargement of the spleen
- growth failure or poor performance at school
- diminished exercise tolerance
- failure of secondary development in parallel with bone age
- severe bone changes
- pregnancy
- infection
- other specific complications: heart failure, pulmonary complications, hypertension, thromboembolic disease, leg ulcers, priapism
Reference:
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