Epidemiology
- peak incidence of non-Hodgkin's lymphoma occurs between 50 and 70 years (67% of of cases occur in patients aged over 60 years). However all ages can be affected (1)
- in the UK;
- NHL is the seventh most frequently diagnosed cancer (2)
- there is a very small male predominance compared to females
- there are around 13,600 new non-Hodgkin lymphoma cases every year, that's 37 every day, accounting for 4% of all new cancer cases (2017-2019) (1)
- there are 5,000 non-Hodgkin lymphoma deaths every year (2021-2023)
- since the early 1990s, non-Hodgkin lymphoma incidence rates have increased by almost a third (30%) in the UK (1)
- in Western Europe and the USA non-Hodgkin's lymphomas account for 55-60% of all malignant lymphomas
- presenting features include lymphadenopathy, hepatosplenomegaly, weight loss, fatigue and night sweats
- 40% of patients present with tumour outside lymph glands
Reference:
- Cancer Research UK. Non Hodgkin's Lymphoma statistics 2025 (online)
- NICE. Non-Hodgkin’s lymphoma: diagnosis and management. NICE guideline NG52. Published July 2016
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