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Intravenous fluids and allopurinol are the mainstay of prophylaxis and treatment of the tumour lysis syndrome.

Rasburicase is recommended for high-risk patients or patients with impaired renal function (1)

Reference:

  • Puri I, Sharma D, Gunturu KS, Ahmed AA. Diagnosis and management of tumor lysis syndrome. J Community Hosp Intern Med Perspect. 2020 Jun 14;10(3):269-272

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