This site is intended for healthcare professionals

CPD
CPD
Pro
Pro
Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Go to /pro/cpd-dashboard page

This page is worth 0.05 CPD credits. CPD dashboard

Go to /account/subscription-details page

This page is worth 0.05 CPD credits. Upgrade to Pro

Prognosis

Authoring team

PCP occurring in a patient is an indicator of something going seriously wrong elsewhere.

A poor prognosis is anticipated by the administration of prophylactic antibiotics (co-trimoxazole and inhaled pentamidine) to people with known HIV infection as their CD4 positive count falls below 200.

Overall in-hospital mortality rates are 15% for HIV-infected patients and 50% in some HIV-uninfected patients (1) but one 17-year retrospective study found in-hospital mortality rates of 25.4%, increasing to 58% if ICU admission was required. (2)

References

  1. Cilloniz C, Dominedo C, Alvarez-Martinez MJ, et al; Pneumocystis pneumonia in the twenty-first century: HIV-infected versus HIV-uninfected patients. Expert Rev Anti Infect Ther. 2019 Oct;17(10):787-801
  2. Schmidt JJ, Lueck C, Ziesing S, et al. Clinical course, treatment and outcome of Pneumocystis pneumonia in immunocompromised adults: a retrospective analysis over 17 years. Crit Care. 2018 Nov 19;22(1):307

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.