Vertical transmission can be reduced if HIV is detected before or during pregnancy.
The risk of transmission of HIV from mother to newborn is around 20% which can be reduced to less than 1% with appropriate interventions (1). Interventions used in preventing vertical transmission are:
Zidovudine treatment reduces this risk to 8%. The regimen consists of:
A trial by Lallement et al. suggests that prolonged zidovudine therapy of the infant may not have additional benefit if the mother has received a long regimen of zidovudine during pregnancy. Conversely if the antenatal treatment period is shortened, the six week course for the infant is likely to be beneficial.
In countries with adequate resources combination drugs are now widely used.
Reference:
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