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Aseptic meningitis

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Aseptic meningitis is a term used to refer to conditions where there are features of meningeal inflammation, but no bacterial growth from cerebrospinal fluid.

It is a subset of meningitis characterized by negative cerebrospinal fluid pleocytosis with a negative Gram stain and sterile bacterial cultures. Diagnosis is based on the presence of CSF pleocytosis, indicated by a CSF white blood cell count greater than 5 cells/mm3 .

The term covers a variety of aetiologies, some of which are certainly infectious, and it is for this reason that the description is less frequently used these days.

Reference

  1. Tattevin P et al. Aseptic meningitis. Rev Neurol (Paris). 2019 Sep-Oct;175(7-8):475-480

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