Charcot-Bouchard aneurysms are microaneurysms 0.8-1.0 mm in diameter. They are the principal cause of primary intracerebral haemorrhage and commonly arise at the bifurcation of small arteries that lie deep within the brain parenchyma.
They occur at well defined sites, the basal ganglia, pons, cerebellum and subcortical white matter.
They are associated with long standing hypertension and result from infiltration of the arterial walls by lipid and hyaline material - a process referred to as hypertensive lipohyalinosis.
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