Cardiac abnormalities are a significant cause of death in patients with Duchenne muscular dystrophy.
The clinical course may be prolonged with progressive cardiac failure or death may come suddenly.
Electrocardiographic abnormalities are often the first sign:
Radiographic abnormalities may be masked by scoliosis and a high diaphragm.
There is often a sinus tachycardia or other arrhythmia.
Echocardiography may demonstrate hypokinesia of the basal left ventricle.
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