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Criterion F

Authoring team

Either of the following:

  • evidence of causative Alzheimer disease genetic mutation from family history or genetic testing
  • all three of the following are present:
    • clear evidence of decline in memory and learning and at least one other cognitive domain
    • steadily progressive, gradual decline in cognition, without extended plateaus
    • no evidence of mixed etiology (i.e. absence of other neurodegenerative disorders or cerebrovascular disease, or another neurological, mental, or systemic disease or condition likely contributing to cognitive decline.

Reference:

  • (1) American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), American Psychiatric Association, Arlington, VA 2013.

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