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Diagnosis

Authoring team

diagnosis

Patients present with the classical clinical picture of dorsiflexion and eversion of the foot, and of extension of the toes, resulting in a foot drop and a characteristic slapping gait (1).

Obtaining a thorough medical history is important:

  • inquire about the possibility of external pressure of the nerve
    • habitual leg crossing, habitual or prolonged squatting or kneeling (may be work related)
    • confinement to bed
    • use of leg brace or recent plaster cast below the knee
    • use of leg positioning or leg supports during recent surgery
    • other causes of compression at the fibular neck

  • check for any precipitating factor
    • recent weight loss (“slimmer’s palsy”)
    • overstretched peroneal nerve (owing to ankle strain or prolonged leg stretching)
    • masses in the popliteal space (for example, Baker’s cysts)

  • identify other causes of neuropathy or mononeuritis multiplex from medical history e.g. - diabetes, alcohol misuse, vitamin B12 deficiency, or chemotherapy

  • exclude acute trauma or surgery causing direct injury to the nerve

  • inquire about other weakness or sensory problems of the leg(s), lower back, or arms

    • painless foot drop without any associated neurological symptoms is almost always due to peroneal monomeuropathy

    • painful footdrop may be caused by L5 radiculopathy, trauma, lumbar plexopathy, or mononeuritis multiplex

Physical examination of the patient:

  • examine
    • patient’s gait
      • severe weakness of the dorsiflexion muscles may cause a high stepping gait (to avoid dragging of the foot)
      • observe while the patient is walking on the heels and toes and if there is difficulty walking on the heel, peripheral neuropathy is the likely cause

    • patient’s legs
      • signs of trauma like swelling or erythema which may suggest compartment syndrome
      • fasciculations in legs and arms –may be due to a more extensive neurological problem (such as motor neurone disease)

    • for reduced pain (pin prick) sensation and light touch in the (lower) legs and feet
      • deep peroneal nerve lesions will cause sensory abnormalities only in the first web space while abnormalities in the anterolateral aspect of the lower leg and the foot dorsum may indicate a superficial peroneal nerve lesion
        • classic textbook description of sensory loss is usually not seen except in total nerve laceration
        • generally sensory loss is restricted to the dorsum of the foot and some toes while in some patients sensory symptoms or signs are absent

  • assess strength of
    • foot dorsiflexion and eversion - peroneal nerve
    • foot plantar flexion and inversion - tibial nerve
    • hip abduction - superior gluteal nerve, L5 nerve root

  • check for signs indicating upper motor neurone disease
    • knee and Achilles’ tendon reflexes for hyper-reflexia and plantar response for Babinski’s sign
  • assess for local tenderness along the course of the common peroneal nerve and for pressure neuropathy by eliciting Tinel’s sign (1,2)

Patients with isolated peroneal mononeuropathy will

  • present with weakness of foot dorsiflexion or eversion (or both).
  • normal reflexes and absent leg pain, swelling, or erythema (2)

Electromyography or nerve conduction studies may be considered to confirm the diagnosis after careful examination of the patient (1,2)

Reference:


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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