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Prevention of recurrence of neural tube defect

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Women who have previously given birth to a baby with a neural tube defect should be offered folic acid 5 mg daily prior to conception and up to the twelfth week of pregnancy. They should also be encouraged to eat foods rich in folate.

Folic acid 5 mg is only available on prescription. Folic acid appears to be safe at these high doses - 20 times the recommended dose for healthy, non-pregnant women - and nevertheless, the probability of preventing recurrence far outweighs the risk to the mother.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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