Alcohol may affect the metabolism of drugs by the liver microsomal enzymes.
If there is an acute 'binge' consumption of alcohol then the metabolism of some drugs may be affected by competition for microsomal enzymes. Alternatively, a regular alcohol consumption of more than 25 units a day induces liver microsomal enzymes and so can increase the rate of drug metabolism.
Important reactions can occur with warfarin, phenytoin and tolbutamide.
Alcohol may add to the CNS depressant effects of drugs such as anxiolytics, opioid analgesics, hypnotics, antipsychotics, antidepressants, antiepileptics and H1-antihistamines.
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.